Crohn's disease is an autoimmune disease which involves chronic inflammation of the gastrointestinal tract. The main symptoms of Crohn's disease are abdominal pain, fever, fatigue and persistent, watery diarrhea. Symptoms range from mild to severe, and can come and go with periods of flare-ups.

In this German study, 51 patients with mild to moderately active Crohn's disease had a decrease in disease activity after receiving 10 sessions of acupuncture. Study members also showed an improvement in general well-being and reported an improvement in quality of life.